Article
Development of quinoxaline 1, 4-dioxides resistance in Escherichia coli and molecular change under resistance selection.
PloS one - 1 Jan 2012
Guo Wentao, Hao Haihong, Dai Menghong, Wang Yulian, Huang Lingli, Peng Dapeng, Wang Xu, Wang Hailan, Yao Min, Sun Yawei, Liu Zhenli, Yuan Zonghui
Abstract excerpt
Quinoxaline 1, 4-dioxides (QdNOs) has been used in animals as antimicrobial agents and growth promoters for decades. However, the resistance to QdNOs in pathogenic bacteria raises worldwide concern but it is barely known. To explore the molecular mechanism involved in development of QdNOs resistance in Escherichia coli, 6 strains selected by QdNOs in vitro and 21 strains isolated from QdNOs-used swine farm were...
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