Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcriptomics profiling of blood CD4 and CD8 T-cells in narcolepsy type I

23 Nov 2023

Abstract excerpt

Background: Narcolepsy Type I (NT1) is a rare, life-long sleep disorder arising as a consequence of the extensive destruction of orexin-producing hypothalamic neurons. The mechanisms involved in the destruction of orexin neurons are not yet elucidated but the association of narcolepsy with environmental triggers and genetic susceptibility (strong association with the HLA, TCRs and other immunologically-relevant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Restless Legs Syndrome Research
Share to Sleep and related disorders
Share to Sleep and Wakefulness Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38077397
DOI: 10.3389/fimmu.2023.1249405

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcriptomics profiling of blood CD4 and CD8 T-cells in narcolepsy type IPMID 38077397Read ↗

The Role of T Cells in the Pathogenesis of Narcolepsy Type 1: A Narrative Review.Semantic proximity Read ↗

High-dimensional single-cell analysis reveals the immune signature of narcolepsy.Semantic proximity Read ↗

Narcolepsy risk loci outline role of T cell autoimmunity and infectious triggers in narcolepsySemantic proximity Read ↗

Multiomics analysis of narcolepsy T cells: global hypomethylation linked to T cell proliferationSemantic proximity Read ↗

The immunopathogenesis of narcolepsy type 1.Semantic proximity Read ↗

Narcolepsy risk loci are enriched in immune cells and suggest autoimmune modulation of the T cell receptor repertoireSemantic proximity Read ↗

LC-MS/MS-Based Proteomics Approach for the Identification of Candidate Serum Biomarkers in Patients with Narcolepsy Type 1Semantic proximity Read ↗

Common variants in P2RY11 are associated with narcolepsy.Semantic proximity Read ↗

The autoimmune basis of narcolepsy.Semantic proximity Read ↗

Changes in the transcriptome of circulating immune cells of a New Zealand cohort with myalgic encephalomyelitis/chronic fatigue syndromeSemantic proximity Read ↗

Mapping the peripheral immune landscape of Parkinson’s disease patients with single-cell sequencingSemantic proximity Read ↗

Autoimmunity in narcolepsy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.