Article
Prevalence of BRAF p.V600E and Detection Methods in Benign Mixed and Malignant Odontogenic Tumors: A Systematic Review.
Head and neck pathology - 1 Dec 2023
Severino-Lazo Raisa Jordana Geraldine, de Vasconcelos Carvalho Marianne, Campello Camilla Porto, Moraes Sandra Lúcia Dantas, do Egito Vasconcelos Belmiro Cavalcanti, Pellizzer Eduardo Piza
Abstract excerpt
BACKGROUND: The BRAF p.V600E genetic variant facilitates the pathogenesis of various tumors by triggering tumor proliferation and progression. The aim of this study was to analyze the prevalence of BRAF p.V600E in benign mixed epithelial and mesenchymal and malignant odontogenic tumors. In addition, we discussed the different detection methods used to assess for aberrant BRAF. METHODS: This systematic review...
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