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Article

BRAF p.V600E Mutation in Mixed Odontogenic Tumors and Its Clinical Correlation: A Systematic Review and Meta-Analysis.

International dental journal - 1 Feb 2026

Chantarangsu Soranun, Phattarataratip Ekarat, Lam-Ubol Aroonwan

Abstract excerpt

The impact of BRAF p.V600E mutation on the pathogenesis of mixed odontogenic tumors remains uncertain. We conducted a systematic review and meta-analysis to determine the prevalence of BRAF mutation in mixed odontogenic tumors and to evaluate the correlation between this mutation and the clinical characteristics of these lesions. The study protocol was registered in PROSPERO (registration number CRD42025636575)....

Read the complete abstract on PubMed

Topics

Humans
Proto-Oncogene Proteins B-raf
Odontogenic Tumors
Mutation
Jaw Neoplasms

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Identifiers

PMID: 41338120
DOI: 10.1016/j.identj.2025.109302
PMCID: PMC12718460

Genes

BRAF

Variants

Provenance

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