Article
Assembly of novel sequences for Chinese domestic pigs reveals new genes and regulatory variants providing new insights into their diversity.
Genomics - 1 Mar 2024
Du Heng, Diao Chenguang, Zhuo Yue, Zheng Xianrui, Hu Zhengzheng, Lu Shiyu, Jin Wenjiao, Zhou Lei, Liu Jian-Feng
Abstract excerpt
There is an increasing understanding that a reference genome representing an individual cannot capture all the gene repertoire of a species. Here, we conduct a population-scale missing sequences detection of Chinese domestic pigs using whole-genome sequencing data from 534 individuals. We identify 132.41 Mb of sequences absent in the reference assembly, including eight novel genes. In particular, the breeds...
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