Article
Integration of multi-omics data reveals cis-regulatory variants that are associated with phenotypic differentiation of eastern from western pigs.
Genetics, selection, evolution : GSE - 14 Sept 2022
Liu Yuwen, Fu Yang, Yang Yalan, Yi Guoqiang, Lian Jinmin, Xie Bingkun, Yao Yilong, Chen Muya, Niu Yongchao, Liu Lei, Wang Liyuan, Zhang Yongsheng, Fan Xinhao, Tang Yijie, Yuan Pengxiang, Zhu Min, Li Qiaowei, Zhang Song, Chen Yun, Wang Binhu, He Jieyu, Lu Dan, Liachko Ivan, Sullivan Shawn T, Pang Bin, Chen Yaoqing, He Xin, Li Kui, Tang Zhonglin
Abstract excerpt
BACKGROUND: The genetic mechanisms that underlie phenotypic differentiation in breeding animals have important implications in evolutionary biology and agriculture. However, the contribution of cis-regulatory variants to pig phenotypes is poorly understood. Therefore, our aim was to elucidate the molecular mechanisms by which non-coding variants cause phenotypic differences in pigs by combining evolutionary...
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