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Drug addiction and treatment: An epigenetic perspective

2 Dec 2023

Abstract excerpt

Drug addiction is a complex disease affected by numerous genetic and environmental factors. Brain regions in reward pathway, neuronal adaptations, genetic and epigenetic interactions causing transcriptional enhancement or repression of multiple genes induce different addiction phenotypes for varying duration. Addictive drug use causes epigenetic alterations and similarly epigenetic changes induced by environment...

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PMID: 38043446
DOI: 10.1016/j.biopha.2023.115951

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