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Article

NADH improves AIF dimerization and inhibits apoptosis in iPSCs-derived neurons from patients with auditory neuropathy spectrum disorder.

Hearing research - 1 Jan 2024

Qiu Yue, Wang Hongyang, Pan Huaye, Ding Xue, Guan Jing, Zhuang Qianqian, Wu Kaiwen, Lei Zhaoying, Cai Huajian, Dong Yufei, Zhou Hui, Lin Aifu, Wang Qiuju, Yan Qingfeng

Abstract excerpt

Auditory neuropathy spectrum disorder (ANSD) is a hearing impairment involving disruptions to inner hair cells (IHCs), ribbon synapses, spiral ganglion neurons (SGNs), and/or the auditory nerve itself. The outcomes of cochlear implants (CI) for ANSD are variable and dependent on the location of lesion sites. Discovering a potential therapeutic agent for ANSD remains an urgent requirement. Here, 293T stable...

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PMID: 38043402
DOI: 10.1016/j.heares.2023.108919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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