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Article

Multimorbidity, cognitive phenotypes, and Alzheimer's disease plasma biomarkers in older adults: A population-based study.

Alzheimer's & dementia : the journal of the Alzheimer's Association - 1 Mar 2024

Ren Yifei, Li Yuanjing, Tian Na, Liu Rui, Dong Yi, Hou Tingting, Liu Cuicui, Han Xiaolei, Han Xiaodong, Wang Lidan, Vetrano Davide Liborio, Ngandu Tiia, Marengoni Alessandra, Kivipelto Miia, Wang Yongxiang, Cong Lin, Du Yifeng, Qiu Chengxuan

Abstract excerpt

INTRODUCTION: To examine the burden and clusters of multimorbidity in association with mild cognitive impairment (MCI), dementia, and Alzheimer's disease (AD)-related plasma biomarkers among older adults. METHODS: This population-based study included 5432 participants (age ≥60 years); of these, plasma amyloid beta (Aβ), total tau, and neurofilament light chain (NfL) were measured in a subsample (n = 1412). We...

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Identifiers

PMID: 38041805
DOI: 10.1002/alz.13519
PMCID: PMC10984420

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