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Article

Elucidating the causal association between gut microbiota and intrahepatic cholangiocarcinoma through Mendelian randomization analysis

14 Nov 2023

Abstract excerpt

Background Intrahepatic cholangiocarcinoma (ICC) is an aggressive liver cancer with poor prognosis. The gut microbiota has been linked to ICC, but evidence for causality is lacking. Elucidating causal gut microbiota-ICC links could inform prevention and treatment strategies. Materials and methods We performed a bidirectional two-sample Mendelian randomization (MR) study to investigate causal associations between...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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Identifiers

PMID: 38033576
DOI: 10.3389/fmicb.2023.1288525

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