The causality between gut microbiome and liver cirrhosis: a bi-directional two-sample Mendelian randomization analysis

Abstract excerpt

Background and aim Previous studies have reported an association between gut microbiota and cirrhosis. However, the causality between intestinal flora and liver cirrhosis still remains unclear. In this study, bi-directional Mendelian randomization (MR) analysis was used to ascertain the potential causal effect between gut microbes and cirrhosis. Methods Large-scale Genome Wide Association Study (GWAS) data of...

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