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Article

The ferroptosis landscape in acute myeloid leukemia.

Aging - 29 Nov 2023

Ma Zhixin, Ye Wenle, Huang Xin, Li Xia, Li Fenglin, Lin Xiangjie, Hu Chao, Wang Jinghan, Jin Jie, Zhu Bo, Huang Jiansong

Abstract excerpt

Ferroptosis induction through the suppression of glutathione peroxidase 4 (GPX4) and apoptosis-inducing factor mitochondria-associated 2 (AIFM2) has proven to be an effective approach in eliminating chemotherapy-resistant cells of various types. However, a comprehensive understanding of the roles of GPX4 and AIFM2 in acute myeloid leukemia (AML) has not yet been achieved. Using cBioPortal, DepMap, GEPIA,...

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Share to Acute Myeloid Leukemia Research
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Leukemia, Myeloid, Acute

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Source

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Identifiers

PMID: 38032290
DOI: 10.18632/aging.205257
PMCID: PMC10713399

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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