Article
Identification of immunity- and ferroptosis-related signature genes as potential design targets for mRNA vaccines in AML patients.
Aging - 29 Aug 2024
Wang Chaojie, Lv Liping, Ma Ping, Zhang Yangyang, Li Mingyuan, Deng Jiang, Zhang Yanyu
Abstract excerpt
Immune-associated ferroptosis plays an important role in the progression of acute myeloid leukemia (AML); however, the targets that play key roles in this process are currently unknown. This limits the development of mRNA vaccines based on immune-associated ferroptosis for clinical therapeutic applications. In this study, based on the rich data resources of the TCGA-LAML cohort, we analyzed the tumor mutational...
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