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AAV2-antiVEGFscFv gene therapy for retinal neovascularization

29 Oct 2023

Abstract excerpt

Retinal neovascularization (NV) may lead to irreversible vision impairment, the main treatment for which is the inhibition of vascular endothelial growth factor (VEGF). Existing drugs show limited clinical benefits because of their high prices and short half-lives, which increase the financial burden and medical risks to patients. Gene therapy on the basis of adeno-associated viruses is a promising approach to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38027065
DOI: 10.1016/j.omtm.2023.101145

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