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Network models of prostate cancer immune microenvironments identify ROMO1 as heterogeneity and prognostic marker

7 Jan 2022

Abstract excerpt

Prostate cancer (PCa) is the fifth leading cause of death from cancer in men worldwide. Its treatment remains challenging due to the heterogeneity of the tumor, mainly because of the lack of effective and targeted prognostic markers at the system biology level. First, the data were retrieved from TCGA dataset, and valid samples were obtained by consistent clustering and principal component analysis; next, key...

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PMID: 34996995
DOI: 10.1038/s41598-021-03946-w

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