Article
Factor V Leiden and the etiology of inflammatory bowel disease.
Thrombosis and haemostasis - 1 Sept 2007
Spek C Arnold, ten Kate Fiebo J W, te Velde Anje A
Abstract excerpt
Inflammatory bowel disease (IBD) refers to two chronic diseases that cause inflammation of the intestines: ulcerative colitis and Crohn's disease. Patients suffering from IBD have a three-fold increased risk of venous thrombosis compared with matched controls. Importantly, thromboembolic disease is a significant cause of morbidity and mortality in patients with IBD. However, despite several supporting...
Topics
- Animals
- Blood Coagulation
- Body Weight
- Colon
- Dextran Sulfate
- Disease Models, Animal
- Factor V
- Inflammatory Bowel Diseases
- Mice
- Mice, Inbred C57BL
- Mice, Mutant Strains
- Mutation
- Organ Size
- Thrombosis