Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoS

27 Nov 2023

Abstract excerpt

As an enzootic pathogen, the Lyme disease bacterium Borrelia burgdorferi possesses multiple copies of chemotaxis proteins, including two chemotaxis histidine kinases (CHK), CheA1 and CheA2. Our previous study showed that CheA2 is a genuine CHK that is required for chemotaxis; however, the role of CheA1 remains mysterious. This report first compares the structural features that differentiate CheA1 and CheA2 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Vector-borne infectious diseases
Share to Viral Infections and Vectors
Share to Yersinia bacterium, plague, ectoparasites research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38011206
DOI: 10.1371/journal.ppat.1011752

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A chemosensory-like histidine kinase is dispensable for chemotaxis in vitro but regulates the virulence of Borrelia burgdorferi through modulating the stability of RpoSPMID 38011206Read ↗

Borrelia burgdorferi CheY2 Is Dispensable for Chemotaxis or Motility but Crucial for the Infectious Life Cycle of the Spirochete.Semantic proximity Read ↗

The Borrelia burgdorferi CheY3 response regulator is essential for chemotaxis and completion of its natural infection cycle.Semantic proximity Read ↗

Borrelia burgdorferi bbk13 Is Critical for Spirochete Population Expansion in the Skin during Early InfectionSemantic proximity Read ↗

CheX is a phosphorylated CheY phosphatase essential for Borrelia burgdorferi chemotaxis.Semantic proximity Read ↗

Borrelia burgdorferi CheD Promotes Various Functions in Chemotaxis and the Pathogenic Life Cycle of the Spirochete.Semantic proximity Read ↗

Gain-of-function study reveals the pleiotropic roles of serine protease HtrA in <i>Borrelia burgdorferi</i>Semantic proximity Read ↗

Detection of Cytosolic Shigella flexneri via a C-Terminal Triple-Arginine Motif of GBP1 Inhibits Actin-Based Motility.Semantic proximity Read ↗

Cyclic Di-GMP Receptor PlzA Controls Virulence Gene Expression through RpoS in Borrelia burgdorferiSemantic proximity Read ↗

Plasticity in early immune evasion strategies of a bacterial pathogenSemantic proximity Read ↗

Detection of cytosolic <i>Shigella flexneri</i> via a C-terminal triple-arginine motif of GBP1 inhibits actin-based motilitySemantic proximity Read ↗

Borrelia burgdorferi Needs Chemotaxis To Establish Infection in Mammals and To Accomplish Its Enzootic CycleSemantic proximity Read ↗

Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.