Article
CheX is a phosphorylated CheY phosphatase essential for Borrelia burgdorferi chemotaxis.
Journal of bacteriology - 1 Dec 2005
Motaleb M A, Miller Michael R, Li Chunhao, Bakker Richard G, Goldstein Stuart F, Silversmith Ruth E, Bourret Robert B, Charon Nyles W
Abstract excerpt
Motility and chemotaxis are believed to be important in the pathogenesis of Lyme disease caused by the spirochete Borrelia burgdorferi. Controlling the phosphorylation state of CheY, a response regulator protein, is essential for regulating bacterial chemotaxis and motility. Rapid dephosphorylation of phosphorylated CheY (CheY-P) is crucial for cells to respond to environmental changes. CheY-P dephosphorylation...
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