Article
Structure-Based Virtual Screening for Novel Inhibitors Targeting KRAS G12C.
Studies in health technology and informatics - 23 Nov 2023
Ding Yiming
Abstract excerpt
KRAS is a protein that is critical to cell activation, but when it becomes mutated, it can contribute to the development of cancer. There is an urgent need for reliable and effective drugs to treat cancer, and KRAS G12C has been a major focus of research in this area. In this study, we used structure-based virtual screening to search for novel inhibitors that can target KRAS G12C. Specifically, we conducted a...
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