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Article

Factors associated with actionable gene aberrations in pancreatic cancer based on the C-CAT database.

Journal of gastroenterology - 1 Aug 2025

Endo Go, Ishigaki Kazunaga, Nakai Yousuke, Nishio Hiroto, Fukuda Koshiro, Ishida Kota, Takaoka Shinya, Tokito Yurie, Fukuda Rintaro, Noguchi Kensaku, Oyama Hiroki, Suzuki Tatsunori, Sato Tatsuya, Saito Tomotaka, Hamada Tsuyoshi, Miyabayashi Koji, Takahara Naminatsu, Sato Yasuyoshi, Kage Hidenori, Oda Katsutoshi, Fujishiro Mitsuhiro

Abstract excerpt

BACKGROUND: Comprehensive genomic profiling (CGP) tests are increasingly used to explore the genomically matched therapies for solid tumors. The aim of this study is to investigate factors associated with actionable gene aberrations in pancreatic cancer (PC) using real-world data from the Center for Advanced Cancer Genome Therapy (C-CAT) database. METHODS: Among 6768 patients with unresectable and recurrent PC...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 40314773
DOI: 10.1007/s00535-025-02253-9
PMCID: PMC12289854

Genes

CAT
KRAS
PC
ATM
BRAF
BRCA2
ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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