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Article

Enhanced expression of HLA-DR antigens by the human melanoma cell line CaCL 73-36 upon induction of a less differentiated phenotype with bromodeoxyuridine.

Anticancer research - 1 Jan 2000

Kawakubo Y, Liao S K

Abstract excerpt

The effects of bromodeoxyuridine (BUdr) on the in vitro growth, morphology and expression of HLA-DR antigens in the human melanoma line CaCL 73-36 were studied. Treatment of melanoma cells with BUdr resulted in an inhibition of growth with 30-35% reduction in saturation density at 2 micrograms/ml and 50-54% reduction at 4 micrograms/ml. BUdr-treated melanoma cells showed marked morphological changes including...

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PMID: 3800326

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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