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Gestational diabetes in mice induces hematopoietic memory that affects the long-term health of the offspring

21 Nov 2023

Abstract excerpt

Gestational diabetes is a common medical complication of pregnancy that is associated with adverse perinatal outcomes and an increased risk of metabolic diseases and atherosclerosis in adult offspring. The mechanisms responsible for this delayed pathological transmission remain unknown. In mouse models, we found that the development of atherosclerosis in adult offspring born to diabetic pregnancy can be in part...

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PMID: 37988162
DOI: 10.1172/jci169730

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