Pooling isolates to address the diversity in antimicrobial susceptibility of Pseudomonas aeruginosa in cystic fibrosis

Abstract excerpt

ABSTRACT The intrasample diversity in antibiotic resistance of Pseudomonas aeruginosa in people with cystic fibrosis (pwCF) may contribute to the low predictive value of antibiotic susceptibility testing (AST). Since often only few isolates per AST are included, a possible solution to decrease the diversity is pooling isolates, yet a comprehensive study on this approach is lacking. This study aims to characterize...

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