Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling module

14 Nov 2023

Abstract excerpt

BACKGROUND & AIMS: Metabolic dysfunction-associated steatohepatitis (MASH) is linked to insulin resistance and type 2 diabetes and marked by hepatic inflammation, microvascular dysfunction, and fibrosis, impairing liver function and aggravating metabolic derangements. The liver homeostatic interactions disrupted in MASH are still poorly understood. We aimed to elucidate the plasticity and changing interactions of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Liver Disease Diagnosis and Treatment
Share to Liver Diseases and Immunity
Share to Liver physiology and pathology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37972658
DOI: 10.1016/j.jhep.2023.11.001

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single cell-resolved study of advanced murine MASH reveals a homeostatic pericyte signaling modulePMID 37972658Read ↗

Hepatic stellate cell heterogeneity: Functional aspects and therapeutic implicationsSemantic proximity Read ↗

Found in translation—Fibrosis in metabolic dysfunction–associated steatohepatitis (MASH)Semantic proximity Read ↗

Myeloid cells contribute to bystander CD8 T cell accumulation in metabolic-associated steatohepatitis and are sufficient for fibrosisSemantic proximity Read ↗

Single cell multiomics reveals drivers of metabolic dysfunction-associated steatohepatitisSemantic proximity Read ↗

Understanding Macrophage Complexity in Metabolic Dysfunction-associated Steatotic Liver Disease: Transitioning from the M1/M2 Paradigm to Spatial DynamicsSemantic proximity Read ↗

Understanding Macrophage Complexity in Metabolic Dysfunction-Associated Steatotic Liver Disease: Transitioning from the M1/M2 Paradigm to Spatial DynamicsSemantic proximity Read ↗

Single‐cell transcriptome analysis of aging mouse liverSemantic proximity Read ↗

Spatial and Single‐Cell Transcriptomics Reveals the Regional Division of the Spatial Structure of MASH FibrosisSemantic proximity Read ↗

A Human Single-cell Atlas Identifies OLR1+ Scar-associated Macrophages as a Therapeutic Target for Chronic Liver DiseaseSemantic proximity Read ↗

Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cellsSemantic proximity Read ↗

Multiomics analyses decipher intricate changes in the cellular and metabolic landscape of steatotic livers upon dietary restriction and sleeve gastrectomySemantic proximity Read ↗

Temporal Analyses of Postnatal Liver Development and Maturation by Single Cell TranscriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.