Article
Molecular-based classification of endometrial carcinoma in Northern Thailand: impact on prognosis and potential for implementation in resource-limited settings.
BMC women's health - 14 Nov 2023
Dankai Wiyada, Pongsuvareeyakul Tip, Phinyo Phichayut, Tejamai Chontichaporn, Teerapakpinyo Chinachote, Cheewakriangkrai Chalong, Lekawanvijit Suree, Siriaunkgul Sumalee, Khunamornpong Surapan
Abstract excerpt
BACKGROUND: Endometrial carcinoma is molecularly categorized into four subgroups: polymerase-E exonuclease domain-mutant (POLE-mut), mismatch repair-deficient (MMR-d), p53-abnormal (p53-abn), and no specific molecular profile (NSMP). This classification scheme has been included into clinical recommendation for post-operative risk-based management, although there have been few Asian studies on this topic. The...
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