Article
Tumor necrosis factor-alpha -863C/A polymorphism is associated with Guillain-Barré syndrome in Bangladesh.
Journal of neuroimmunology - 15 Sept 2017
Jahan Israt, Ahammad Rijwan U, Farzana Kaniz S, Khalid Mir M, Islam Mohammad B, Rahman Mohammad I, Nahar Shamsun, Kabir Yearul, Mohmmad Quazi D, Islam Zhahirul
Abstract excerpt
Guillain-Barré syndrome (GBS) is a post-infectious autoimmune polyneuropathy regulated by pro- and anti-inflammatory cytokines; TNFA polymorphisms may exert immune pathogenic roles in GBS. We assessed TNFA promoter region polymorphisms (-238G/A, -308G/A, -857C/T, -863C/A) in Bangladeshi patients with GBS (n=300) and healthy controls (n=300) by PCR-RFLP and ASO-PCR. TNFA -863CA was significantly associated with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
