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Article

Muller's genetic load/species extinction hypothesis.

Environmental research - 15 Jan 2024

Calabrese Edward J, Selby Paul B

Abstract excerpt

The genetic load hypothesis of Hermann Muller raised the profound question of possible species extinction, even for humans, following a prolonged accumulation of recessive genes due to ionizing radiation exposure within the population. Two major mouse radiation research teams in the United States provided the most extensive tests of Muller's hypothesis. One group continued its study for more than two decades,...

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PMID: 37952856
DOI: 10.1016/j.envres.2023.117599

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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