Spontaneous mutations recovered as mosaics in the mouse specific-locus test.

doi:10.1073/pnas.93.23.13072

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Article

Spontaneous mutations recovered as mosaics in the mouse specific-locus test.

Proceedings of the National Academy of Sciences of the United States of America - 12 Nov 1996

Russell L B, Russell W L

Abstract excerpt

The specific-locus test (SLT) detects new mutants among mice heterozygous for seven recessive visible markers. Spontaneous mutations can be manifested not only as singleton whole-body mutants in controls (for which we report new data), but as mosaics-either visible (manifesting mottled coat color...

Topics

Animals
Crosses, Genetic
Female
Genes, Recessive
Genetic Markers
Genome
Genotype
Homozygote
Litter Size
Male
Mice
Mice, Inbred C3H
Mice, Inbred Strains
Mice, Mutant Strains
Mosaicism
Mutagenesis

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