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Article

Clinical outcomes of stereotactic biopsy on children with pontine diffuse midline glioma.

Journal of neuro-oncology - 1 Nov 2023

Khan A Basit, Dang Huy Q, Gopakumar Sricharan, Lazaro Tyler, Gadgil Nisha, Baxter Patricia, Malbari Fatema, Aldave Guillermo

Abstract excerpt

INTRODUCTION: Diffuse midline glioma (DMG) of the pons occurs in pediatric patients and carries a dismal prognosis. Biopsy is not necessary for diagnosis but provides information, particularly H3K27M status, with prognostic implications. Additionally, biopsy information may open therapeutic options such as clinical trials that require mutation status. Therefore, we sought to assess the safety of surgical biopsy...

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PMID: 37945818
DOI: 10.1007/s11060-023-04475-4

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