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MicroRNA-200 Loaded Lipid Nanoparticles Promote Intestinal Epithelium Regeneration in Canonical MicroRNA-Deficient Mice

8 Nov 2023

Abstract excerpt

High Resolution Image Download MS PowerPoint Slide Intestinal epithelium undergoes regeneration after injuries, and the disruption of this process can lead to inflammatory bowel disease and tumorigenesis. Intestinal stem cells (ISCs) residing in the crypts are crucial for maintaining the intestinal epithelium’s homeostasis and promoting regeneration upon injury. However, the precise role of DGCR8, a critical...

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PMID: 37939210
DOI: 10.1021/acsnano.3c08030

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