Article
An individualized Bayesian method for estimating genomic variants of hypertension.
BMC genomics - 7 Nov 2023
Rahman Md Asad, Cai Chunhui, Bo Na, McNamara Dennis M, Ding Ying, Cooper Gregory F, Lu Xinghua, Liu Jinling
Abstract excerpt
BACKGROUND: Genomic variants of the disease are often discovered nowadays through population-based genome-wide association studies (GWAS). Identifying genomic variations potentially underlying a phenotype, such as hypertension, in an individual is important for designing personalized treatment; however, population-level models, such as GWAS, may not capture all the important, individualized factors well. In...
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