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Article

Prognosis of CDKN2A germline mutation in patients with familial melanoma: a systematic review and meta-analysis.

Melanoma research - 1 Feb 2024

Taibo Ana, Paradela Sabela, Suanzes-Hernández Jorge, Balboa-Barreiro Vanesa, Amado-Bouza Javier, Fonseca Eduardo

Abstract excerpt

Familial melanoma is defined as melanoma occurring in two or more first-degree relatives by the WHO. Germline mutations are isolated in a subset of them. It is well known that CDKN2A is the most frequently mutated high-risk gene in familial melanoma, however, the prognosis it confers to patients who carry its mutations is still controversial. This review aims to assess whether germline mutations imply a worse...

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Identifiers

PMID: 37924530
DOI: 10.1097/CMR.0000000000000920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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