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Article

In silico SNP prediction of selected protein orthologues in insect models for Alzheimer's, Parkinson's, and Huntington's diseases.

Scientific reports - 3 Nov 2023

Al-Ayari Eshraka A, Shehata Magdi G, El-Hadidi Mohamed, Shaalan Mona G

Abstract excerpt

Alzheimer's, Parkinson's, and Huntington's are the most common neurodegenerative diseases that are incurable and affect the elderly population. Discovery of effective treatments for these diseases is often difficult, expensive, and serendipitous. Previous comparative studies on different model organisms have revealed that most animals share similar cellular and molecular characteristics. The meta-SNP tool...

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PMID: 37923901
DOI: 10.1038/s41598-023-46250-5
PMCID: PMC10624829

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