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Interaction between intratumoral microbiota and tumor mediates the response of neoadjuvant therapy for rectal cancer

12 Oct 2023

Abstract excerpt

Background Previous observations have demonstrated that the response to neoadjuvant chemoradiotherapy (nCRT) is highly variable in patients with locally advanced rectal cancer (LARC). Recent studies focusing on the intratumoral microbiota of colorectal cancer have revealed its role in oncogenesis and tumor progression. However, limited research has focused on the influence of intratumoral microbiota on the nCRT...

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PMID: 37901832
DOI: 10.3389/fmicb.2023.1229888

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