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The role and challenges of intratumoral microbiota in colorectal cancer immunotherapy

7 Aug 2025

Abstract excerpt

Colorectal cancer (CRC) is the third most common malignant tumor globally, and its development is closely related to interactions between the host and microbes. Recent studies have shown that the diversity of intratumoral microbiota significantly influences CRC progression and responses to immune therapy. This influence occurs through mechanisms such as immune microenvironment regulation, metabolic reprogramming,...

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PMID: 40852612
DOI: 10.3389/fphar.2025.1634703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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