Alternative genetic alterations of MYC, BCL2, and/or BCL6 in high‐grade B‐cell lymphoma ( HGBL ) and diffuse large B‐cell lymphoma ( DLBCL ): Can we identify different prognostic subgroups?

Abstract excerpt

High-grade B-cell lymphoma (HGBL)/diffuse large B-cell lymphoma (DLBCL) with rearrangements (R) in MYC and BCL2 and/or BCL6 are correlated with poor prognosis. Little is known about the impact of other genetic alterations (gain (G) or amplification (A)) of these genes. The aim of the study was to investigate whether we can identify new prognostic subgroups. Fluorescence in situ hybridization (FISH) results from...

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