Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

IsolatedMYCcytogenetic abnormalities in diffuse large B-cell lymphoma do not predict an adverse clinical outcome

1 Apr 2015

Abstract excerpt

In this study, we investigated the significance of MYC, BCL2 and BCL6 gene abnormalities in a cohort of 205 diffuse large B-cell lymphoma (DLBCL) patients studied by conventional and/or fluorescence in situ hybridization cytogenetic analysis. Combining these methods, 172 cases (84%) were classified as MYC-, 17 (8%) were MYC+/BCL2-/BCL6-, and 16 (8%) were double/triple-hit lymphomas (i.e. MYC+/BCL2+, MYC+/BCL6+,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Lymphoma Diagnosis and Treatment
Share to Viral-associated cancers and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 25827211
DOI: 10.3109/10428194.2015.1034699

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

IsolatedMYCcytogenetic abnormalities in diffuse large B-cell lymphoma do not predict an adverse clinical outcomePMID 25827211Read ↗

The impact of MYC rearrangements and "double hit" abnormalities in diffuse large B-cell lymphoma.Semantic proximity Read ↗

MYC single-hit large B-cell lymphoma: clinicopathologic difference from MYC-negative large B-cell lymphoma and MYC double-hit/triple-hit lymphoma.Semantic proximity Read ↗

MYC‐associated and double‐hit lymphomas: A review of pathobiology, prognosis, and therapeutic approachesSemantic proximity Read ↗

Further Exploration of the Complexities of Large B-Cell Lymphomas With MYC Abnormalities and the Importance of a Blastoid MorphologySemantic proximity Read ↗

Prognostic impact of diffuse large B-cell lymphoma with extra copies of MYC, BCL2 and/or BCL6: comparison with double/triple hit lymphoma and double expressor lymphomaSemantic proximity Read ↗

MYC protein expression and genetic alterations have prognostic impact in patients with diffuse large B-cell lymphoma treated with immunochemotherapySemantic proximity Read ↗

Alternative genetic alterations of MYC, BCL2, and/or BCL6 in high‐grade B‐cell lymphoma ( HGBL ) and diffuse large B‐cell lymphoma ( DLBCL ): Can we identify different prognostic subgroups?Semantic proximity Read ↗

<i>MYC</i> translocation and/or BCL 2 protein expression are associated with poor prognosis in diffuse large B‐cell lymphomaSemantic proximity Read ↗

Impact of oncogene rearrangement patterns on outcomes in patients with double‐hit non‐Hodgkin lymphomaSemantic proximity Read ↗

MYC Expression in Concert with BCL2 and BCL6 Expression Predicts Outcome in Chinese Patients with Diffuse Large B-Cell Lymphoma, Not Otherwise SpecifiedSemantic proximity Read ↗

Double-hit B-cell lymphomas with BCL6 and MYC translocations are aggressive, frequently extranodal lymphomas distinct from BCL2 double-hit B-cell lymphomas.Semantic proximity Read ↗

Patients with diffuse large B-cell lymphoma of germinal center origin with BCL2 translocations have poor outcome, irrespective of MYC status: a report from an International DLBCL rituximab-CHOP Consortium Program StudySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.