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Article

Association of HLA-A11:01, -A24:02, and -B*18:01 with Prostate Cancer Risk: A Case-Control Study.

International journal of molecular sciences - 20 Oct 2023

Manca Maria Antonietta, Simula Elena Rita, Cossu Davide, Solinas Tatiana, Madonia Massimo, Cusano Roberto, Sechi Leonardo Antonio

Abstract excerpt

The major histocompatibility complex (MHC) loci, the most polymorphic regions within the human genome, encode protein complexes responsible for antigen presentation and CD4+ and CD8+ cell activation. In prostate cancer (PCa), the second most diagnosed cancer in the male population, MHC loci undergo significant changes in their expression patterns, which affect the ability of the immune system to attack and...

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Identifiers

PMID: 37895076
DOI: 10.3390/ijms242015398
PMCID: PMC10607162

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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