Article
Relationship between HLA-DR antigen and HLA-DRB1 alleles and prostate cancer in Japanese men.
International urology and nephrology - 1 Jan 1999
Azuma H, Sada M, Tsuji T, Ueda H, Katsuoka Y
Abstract excerpt
PURPOSE: Human leukocyte antigens (HLA) are cell surface glycoproteins playing a key role in the immune system. In some cancers, changes in major histocompatibility complex (MHC) class I and II expression, usually a reduction or loss of these molecules, appear to provide a mechanism whereby tumour cells may escape host immunity. We investigated the relationship between HLA, especially class II, molecules and...
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