Article
The angiotensin-converting enzyme I/D polymorphism does not impact training-induced adaptations in exercise capacity in patients with stable coronary artery disease.
Scientific reports - 25 Oct 2023
Sjúrðarson Tórur, Kristiansen Jacobina, Nordsborg Nikolai B, Gregersen Noomi O, Lydersen Leivur N, Grove Erik L, Kristensen Steen D, Hvas Anne-Mette, Mohr Magni
Abstract excerpt
Systematic exercise training effectively improves exercise capacity in patients with coronary artery disease (CAD), but the magnitude of improvements is highly heterogeneous. We investigated whether this heterogeneity in exercise capacity gains is influenced by the insertion/deletion (I/D) polymorphism of the angiotensin-converting enzyme (ACE) gene. Patients with CAD (n = 169) were randomly assigned to 12 weeks...
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