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Advances in immunotyping of colorectal cancer

9 Oct 2023

Abstract excerpt

Immunotherapy has transformed treatment for various types of malignancy. However, the benefit of immunotherapy is limited to a minority of patients with mismatch-repair-deficient (dMMR) and microsatellite instability-high (MSI-H) (dMMR-MSI-H) colorectal cancer (CRC). Understanding the complexity and heterogeneity of the tumor immune microenvironment (TIME) and identifying immune-related CRC subtypes will improve...

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PMID: 37876934
DOI: 10.3389/fimmu.2023.1259461

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