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Metabolomic biomarkers of habitual B vitamin intakes unveil novel differentially methylated positions in the human epigenome

19 Oct 2023

Abstract excerpt

BACKGROUND: B vitamins such as folate (B9), B6, and B12 are key in one carbon metabolism, which generates methyl donors for DNA methylation. Several studies have linked differential methylation to self-reported intakes of folate and B12, but these estimates can be imprecise, while metabolomic biomarkers can offer an objective assessment of dietary intakes. We explored blood metabolomic biomarkers of folate and...

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PMID: 37858220
DOI: 10.1186/s13148-023-01578-7

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