Article
The food safety assessment of all-female common carp (Cyprinus carpio) (cyp17a1+/-;XX genotype) generated using genome editing technology.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Nov 2023
Chen Guanghui, Huang Jianfei, Jia Jingyi, Lou Qiyong, Shi Chuang, Yasheng Musha, Zhao Yijia, Yuan Qingyun, Tang Kui, Liu Xiaolong, Wang Zhengkai, Jiang Donghuo, Qian Xueqiao, Yin Zhan, Zhai Gang
Abstract excerpt
There are several technical challenges and public issues concerning genome editing applications before they become viable in commercial aquaculture. Recently, we developed a novel strategy to generate all-female (AF) common carp, which exhibited a growth advantage over the control carp, using genetic editing through single gene-targeting manipulation. Here, we found that the body weight of the AF common carp was...
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