Article
Distinct non-synonymous mutations in cytochrome b highly correlate with decoquinate resistance in apicomplexan parasite Eimeria tenella.
Parasites & vectors - 17 Oct 2023
Hao Zhenkai, Chen Junmin, Sun Pei, Chen Linlin, Zhang Yuanyuan, Chen Wenxuan, Hu Dandan, Bi Feifei, Han Zhenyan, Tang Xinming, Suo Jingxia, Suo Xun, Liu Xianyong
Abstract excerpt
BACKGROUND: Protozoan parasites of the genus Eimeria are the causative agents of chicken coccidiosis. Parasite resistance to most anticoccidial drugs is one of the major challenges to controlling this disease. There is an urgent need for a molecular marker to monitor the emergence of resistance against anticoccidial drugs, such as decoquinate. METHODS: We developed decoquinate-resistant strains by successively...
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