Article
Novel mutations associated with resistance to Bacillus sphaericus in a polymorphic region of the Culex quinquefasciatus cqm1 gene.
Applied and environmental microbiology - 1 Sept 2012
Chalegre Karlos Diogo de Melo, Romão Tatiany Patrícia, Tavares Daniella Aliny, Santos Eloína Mendonça, Ferreira Lígia Maria, Oliveira Cláudia Maria Fontes, de-Melo-Neto Osvaldo Pompílio, Silva-Filha Maria Helena Neves Lobo
Abstract excerpt
Bin toxin from Bacillus sphaericus acts on Culex quinquefasciatus larvae by binding to Cqm1 midgut-bound receptors, and disruption of the cqm1 gene is the major cause of resistance. The goal of this work was to screen for a laboratory-selected resistance cqm1(REC) allele in field populations in the city of Recife, Brazil, and to describe other resistance-associated polymorphisms in the cqm1 gene. The cqm1(REC)...
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