Article
Target gene mutation discovery and amplicon sequencing for evaluating maduramicin resistance in Eimeria tenella.
Communications biology - 20 Dec 2025
Gao Yang, Li Xiaojin, Yuan Meng-di, Guo Qingbin, Zhang Sixin, Wang Zixuan, Xie Yuehua, Han Hongyu, Liu Xianyong, Zhang Yuanyuan, Suo Xun
Abstract excerpt
Anticoccidial drug resistance in Eimeria spp. presents a growing threat to global poultry health and food security, necessitating robust molecular tools for resistance surveillance. In this study, we report the identification and functional validation of a single nucleotide mutation (c.1255 C > T) in the ETH2_0402100 gene of Eimeria tenella that confers resistance to maduramicin, a widely used ionophore...
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