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Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131

1 Feb 2018

Abstract excerpt

Background: Epidemiological studies point to the gut as a key reservoir of multidrug resistant Escherichia coli multilocus sequence type 131 (ST131), a globally dominant pathogenic clone causing urinary tract and bloodstream infections. Here we report a detailed investigation of its intestinal lifestyle. Methods: Clinical ST131 isolates and type 1 fimbriae null mutants were assessed for colonization of human...

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PMID: 29471349
DOI: 10.1093/infdis/jiy031

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Related research

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Intestinal Colonization Traits of Pandemic Multidrug-Resistant Escherichia coli ST131PMID 29471349Read ↗

Extensive Household Outbreak of Urinary Tract Infection and Intestinal Colonization due to Extended-Spectrum β-Lactamase-Producing Escherichia coli Sequence Type 131.Semantic proximity Read ↗

Transmission dynamics of Escherichia coli sequence type 131 in households – a “One Health” prospective cohort studySemantic proximity Read ↗

Comparative Genomic Analysis of Globally Dominant ST131 Clone with Other Epidemiologically Successful Extraintestinal Pathogenic Escherichia coli (ExPEC) Lineages.Semantic proximity Read ↗

Insights into a multidrug resistant Escherichia coli pathogen of the globally disseminated ST131 lineage: genome analysis and virulence mechanisms.Semantic proximity Read ↗

The <i>cnf1</i> gene is associated to an expanding <i>Escherichia coli</i> ST131 <i>H30</i> Rx/C2 sublineage and confers a competitive advantage for host colonizationSemantic proximity Read ↗

Success of <i>Escherichia coli</i> O25b:H4 ST131 clade C associated with a decrease in virulenceSemantic proximity Read ↗

Emergence of Enteroaggregative Escherichia coli within the ST131 Lineage as a Cause of Extraintestinal InfectionsSemantic proximity Read ↗

Global dissemination of a multidrug resistant Escherichia coli clone.Semantic proximity Read ↗

Evolution of extended-spectrum β-lactamase-producing ST131 <i>Escherichia coli</i> at a single hospital over 15 yearsSemantic proximity Read ↗

Genomic analysis uncovers a phenotypically diverse but genetically homogeneous Escherichia coli ST131 clone circulating in unrelated urinary tract infections.Semantic proximity Read ↗

Multi-drug resistant <i>E. coli</i> displace commensal <i>E. coli</i> from the intestinal tract, a trait associated with elevated levels of genetic diversity in carbohydrate metabolism genesSemantic proximity Read ↗

Multidrug-resistant E. coli encoding high genetic diversity in carbohydrate metabolism genes displace commensal E. coli from the intestinal tract.Semantic proximity Read ↗

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