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Article

Precision Therapy for a Chinese Family With Maturity-Onset Diabetes of the Young.

Frontiers in endocrinology - 1 Jan 2021

Li Juyi, Shu Meng, Wang Xiufang, Deng Aiping, Wen Chong, Wang Juanjuan, Jin Si, Zhang Hongmei

Abstract excerpt

Objective: To determine the pathogenic gene and explore the clinical characteristics of maturity-onset diabetes of the young type 2 (MODY2) pedigree caused by a mutation in the glucokinase (GCK) gene. Methods: Using whole-exome sequencing (WES), the pathogenic gene was detected in the proband-a 20-year-old young man who was accidentally found with hyperglycemia, no ketosis tendency, and a family history of...

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Identifiers

PMID: 34421822
DOI: 10.3389/fendo.2021.700342
PMCID: PMC8374143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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