Article
Characterization of 164 patients with NRAS mutated non-small cell lung cancer (NSCLC).
Lung cancer (Amsterdam, Netherlands) - 1 Dec 2023
Dehem Agathe, Mazieres Julien, Chour Ali, Guisier Florian, Ferreira Marion, Boussageon Maxime, Girard Nicolas, Moro-Sibilot Denis, Cadranel Jacques, Zalcman Gérard, Ricordel Charles, Wislez Marie, Munck Camille, Poulet Claire, Gauvain Clément, Descarpentries Clotilde, Wasielewski Eric, Cortot Alexis B, Baldacci Simon
Abstract excerpt
BACKGROUND: NRAS mutations are observed in less than 1% of non-small cell lung cancer (NSCLC). Clinical data regarding this rare subset of lung cancer are scarce and response to systemic treatment such as chemotherapy or immune checkpoint inhibitors (ICI) has never been reported. METHODS: All consecutive patients with an NRAS mutated NSCLC, diagnosed between August 2014 and November 2020 in 14 French centers,...
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