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2-thiouridine is a broad-spectrum antiviral nucleoside analogue against positive-strand RNA viruses

13 Oct 2023

Abstract excerpt

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections are causing significant morbidity and mortality worldwide. Furthermore, over 1 million cases of newly emerging or re-emerging viral infections, specifically dengue virus (DENV), are known to occur annually. Because no virus-specific and fully effective treatments against these or many other viruses have been approved, there is an urgent need...

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PMID: 37831739
DOI: 10.1073/pnas.2304139120

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